UT Southwestern Medical Center scientists say they are the first to have successfully blocked tumor development in a genetic mouse model of an incurable human cancer.
“To my knowledge, this is the first time that a mouse model of a genetically defined malignant human cancer has been generated in which the formation of the tumor from beginning to end can be monitored and in which blocking the pathway cures the mouse of the tumor,” said Dr. Luis Parada, chair of the department of developmental biology at UT Southwestern and senior author of the study published in Cell and online. The study’s first author is Dr. Wei Mo, a postdoctoral researcher in the department.
